Process of producing a nutritive substance from blood.



Usu'rsn STATES Patented December. 27, 1904:.

Furnsir @rrrca GESELLSCHAFT FUR HUNGARY.

PRUGESS @F PRQDUGENG A NUTFEETEVE SPEGIFIGATIQN forming part (if Letters lPatent No.

CHEMISGHE INDUSTRIE, OF VIENNA, AUSTRIA suesraucr; snore Broom 778,783, dated. December 27, 1904-,

Application filed July 26, 1903. Serial No. 166,966.

To all whom it may concern:

Be it known thatLJUnws HOFMEIER, a sub ject of the Emperor of Austria-Hungary, residing at Brahmsplatz 7 Vienna IV, in the Province of Lower Austria and Empire of Austria-Hungary, have invented certain new and useful Improvements in-Processes of Producing Nutritive Substances from Blood, of which the following is a specification.

The object of the present invention isa process of producing from blood a nutritive substance which contains iron and phosphorus and has the valuable property to produce no hemotin when digested with gastric juice in contrast with hemoglobin and the so-called V native hemoglobin preparations which, as

well known, produce hematin in insoluble state when treated with gastric juice.

The present process consists, essentially, in 2 digesting coagulated blood or a solution 0t hemoglobin at a temperature of about 60 to 90 centigrade with an alkaline solution until a proof of albuminate precipitated therefrom with diluted acids no longer produces flocks 2 5 when digested with artificial gastric juice, whcreafterhydrochloric acid is added until the albuminatcs are wholly precipitated.

. he best manner of proceeding for producing the said nutritive'matter is the following 3 one: One kilogram of coagulated blood, blood corpusclcs, or a twenty-per-cent. solution of hemoglobin is mixed with fifty cubic'centimeters of a solution of sodium hydrate of to v Baum, and after twenty-four hours this 35 mixture is heated to a temperature of to centigrade. The said mixture, which has been liquefied by heating, is kept one or two hours at the aforesaid temperature, and after this time hydrochloric acid'is added until the whole mass shows acid reaction upon litmus. The albuminates precipitated thereby and containing iron and phosphorus are separated by pressing, if necessary, redissolved and pro.- cipitated, and dried at low temperature.

The nutritious matter produced iii the described way is dissolved completely and without residuum when digested with gastric juice, in consequence ofwhich the iron contained in the preparation is easily and completely ahsorbed by the organism.

Having now described my invention, what 1 claim as new, and desire to secure by Letters.

Patent, is-

Aprocess for producing a nutritive substance from blood consisting in treating coagulated blood at a temperature of .60 to 9Q centigrade with an alkaline solution until a proof of albuminate precipitated therefrom with diluted acids no longer when digested with artificial gastric juice, adding then hydrochloric acid, until the al-.- buminates are wholly precipitated, separating the precipitated albuminates by pressing and produces flocks drying them at low temperature, substantially as described and for the purpose set forth.

Signed at Vienna, in the Province of Lower Austria and Empire of Austria-Hungary, this 9th day of July, A. D. 1903.

JULIUS HOFMEIER. Witnesses:

Fnrrs Focus, ALFRED \RAUHAUPT. 

